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pentobarbital will lower the level or effect of triazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital decreases levels of panobinostat by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can lower panobinostat concentrations by ~70% and result in remedy